Note: TD in the Higher column indicates a Trend Difference for the continuous variable.
Executive Summary
Maternal Preconception Study
Restraint Stress Effect on Serum Corticosterone
Introduction
The results of the analysis are presented using the following structure:
- Searchable High‑Level Summary: Provides a brief overview of the key findings from our analysis with a table of effects
- Visualisation, Descriptive Statistics and Diagnostics by Variable: Exploratory data analysis and model diagnostics for each behavioral measure
- Searchable ROPE Analysis Table: Model diagnostics to check the fit of the models
Effects of Interest
- No meaningful effects were found.
Searchable High‑Level Summary
Enter search terms in the column headers to filter the table below
Visualisation, Descriptive Statistics and Diagnostics by Variable
Bar Plot
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\(labels\)labels$x [1] “Time”
\(labels\)y [1] “Corticosterone (ng/mL)”
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| Corticosterone by Grouping Variables | |||||||
| Diet | n | Mean | SD | Min | Max | % of Zeros | Zero Flag |
|---|---|---|---|---|---|---|---|
| Control | 32.0 | 259.1 | 131.2 | 47.0 | 501.1 | 0.0 | |
| CR25 | 32.0 | 224.7 | 129.6 | 101.0 | 577.0 | 0.0 | |
| CRA | 32.0 | 193.7 | 66.9 | 112.4 | 421.0 | 0.0 | |
| CRV | 32.0 | 245.1 | 147.6 | 79.0 | 725.0 | 0.0 | |
| Warning symbols: * = >40% zeros in this group, ! = >20% zeros in entire sample Either flag triggers the use of a binary choice model. | |||||||
Summary Table
| Model Summary | |||||
| Family: lognormal | |||||
| Parameter | Estimate | Std. Error | 2.5% CI | 97.5% CI | Type |
|---|---|---|---|---|---|
| Fixed Effects | |||||
| Intercept | 5.449 | 0.161 | 5.132 | 5.769 | Fixed Effects |
| DietCR25 | −0.204 | 0.226 | −0.653 | 0.238 | Fixed Effects |
| DietCRA | −0.265 | 0.227 | −0.714 | 0.184 | Fixed Effects |
| DietCRV | −0.003 | 0.230 | −0.459 | 0.445 | Fixed Effects |
| Time | −0.001 | 0.002 | −0.004 | 0.003 | Fixed Effects |
| DietCR25:Time | 0.001 | 0.003 | −0.004 | 0.006 | Fixed Effects |
| DietCRA:Time | 0.001 | 0.002 | −0.003 | 0.006 | Fixed Effects |
| DietCRV:Time | −0.001 | 0.002 | −0.006 | 0.004 | Fixed Effects |
Posterior Check
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Convergence
| Effect | Median | [95% HDI] | Direction Prob. | ROPE % |
|---|---|---|---|---|
| Diet: Control vs CR25 | ||||
| Diet: Control vs CR25 | 0.13 | [-0.26, 0.52] | 76.00 | 14.85 |
| Diet: Control vs CRA | ||||
| Diet: Control vs CRA | 0.19 | [-0.18, 0.59] | 84.25 | 11.65 |
| Diet: Control vs CRV | ||||
| Diet: Control vs CRV | 0.05 | [-0.34, 0.42] | 61.75 | 20.25 |
| Diet: CR25 vs CRA | ||||
| Diet: CR25 vs CRA | 0.06 | [-0.34, 0.44] | 61.90 | 18.70 |
| Diet: CR25 vs CRV | ||||
| Diet: CR25 vs CRV | -0.08 | [-0.51, 0.30] | 64.95 | 18.20 |
| Diet: CRA vs CRV | ||||
| Diet: CRA vs CRV | -0.13 | [-0.51, 0.26] | 76.55 | 15.60 |
| Effect | Median | [95% HDI] | Direction Prob. | ROPE % |
|---|---|---|---|---|
| Time: Overall Change | ||||
| Time: Overall Change 0 - 30 | 0.00 | [-0.06, 0.05] | 57.15 | 92.65 |
| Time: Overall Change 30 - 60 | 0.00 | [-0.06, 0.05] | 57.15 | 92.65 |
| Time: Overall Change 60 - 120 | -0.01 | [-0.12, 0.10] | 57.15 | 64.90 |
| Effect | Median | [95% HDI] | Direction Prob. | ROPE % |
|---|---|---|---|---|
| Time × Diet: Control - CR25 | ||||
| Time × Diet: Control - CR25 0 | 0.20 | [-0.21, 0.65] | 81.70 | 11.80 |
| Time × Diet: Control - CR25 30 | 0.17 | [-0.23, 0.54] | 78.80 | 14.95 |
| Time × Diet: Control - CR25 60 | 0.12 | [-0.25, 0.53] | 73.75 | 15.65 |
| Time × Diet: Control - CR25 120 | 0.04 | [-0.47, 0.61] | 56.00 | 13.55 |
| Time × Diet: Control - CRA | ||||
| Time × Diet: Control - CRA 0 | 0.27 | [-0.16, 0.75] | 88.10 | 7.70 |
| Time × Diet: Control - CRA 30 | 0.22 | [-0.16, 0.64] | 87.10 | 10.70 |
| Time × Diet: Control - CRA 60 | 0.17 | [-0.23, 0.56] | 81.40 | 14.20 |
| Time × Diet: Control - CRA 120 | 0.08 | [-0.44, 0.62] | 63.50 | 15.40 |
| Time × Diet: Control - CRV | ||||
| Time × Diet: Control - CRV 0 | 0.00 | [-0.49, 0.42] | 50.05 | 16.60 |
| Time × Diet: Control - CRV 30 | 0.03 | [-0.38, 0.42] | 57.20 | 18.75 |
| Time × Diet: Control - CRV 60 | 0.07 | [-0.35, 0.44] | 62.60 | 17.55 |
| Time × Diet: Control - CRV 120 | 0.13 | [-0.40, 0.63] | 68.00 | 13.05 |
| Time × Diet: CR25 - CRA | ||||
| Time × Diet: CR25 - CRA 0 | 0.06 | [-0.41, 0.49] | 60.80 | 16.00 |
| Time × Diet: CR25 - CRA 30 | 0.07 | [-0.33, 0.47] | 62.40 | 16.40 |
| Time × Diet: CR25 - CRA 60 | 0.06 | [-0.34, 0.47] | 61.90 | 18.25 |
| Time × Diet: CR25 - CRA 120 | 0.05 | [-0.50, 0.59] | 57.70 | 13.25 |
| Time × Diet: CR25 - CRV | ||||
| Time × Diet: CR25 - CRV 0 | -0.20 | [-0.71, 0.23] | 81.45 | 11.90 |
| Time × Diet: CR25 - CRV 30 | -0.13 | [-0.54, 0.26] | 73.05 | 17.30 |
| Time × Diet: CR25 - CRV 60 | -0.06 | [-0.44, 0.35] | 60.15 | 18.25 |
| Time × Diet: CR25 - CRV 120 | 0.08 | [-0.49, 0.61] | 62.80 | 13.20 |
| Time × Diet: CRA - CRV | ||||
| Time × Diet: CRA - CRV 0 | -0.27 | [-0.74, 0.18] | 87.40 | 7.80 |
| Time × Diet: CRA - CRV 30 | -0.19 | [-0.60, 0.21] | 83.25 | 11.90 |
| Time × Diet: CRA - CRV 60 | -0.11 | [-0.52, 0.28] | 71.45 | 17.30 |
| Time × Diet: CRA - CRV 120 | 0.03 | [-0.54, 0.49] | 53.90 | 14.35 |
| Effect | Median | [95% HDI] | Direction Prob. | ROPE % |
|---|---|---|---|---|
| Time: Control | ||||
| Time: Control 0 - 30 | -0.02 | [-0.12, 0.08] | 63.40 | 61.15 |
| Time: Control 30 - 60 | -0.02 | [-0.12, 0.08] | 63.40 | 61.15 |
| Time: Control 60 - 120 | -0.04 | [-0.25, 0.16] | 63.40 | 33.35 |
| Time: CR25 | ||||
| Time: CR25 0 - 30 | 0.02 | [-0.10, 0.13] | 66.35 | 57.90 |
| Time: CR25 30 - 60 | 0.02 | [-0.10, 0.13] | 66.35 | 57.90 |
| Time: CR25 60 - 120 | 0.04 | [-0.19, 0.25] | 66.35 | 31.15 |
| Time: CRA | ||||
| Time: CRA 0 - 30 | 0.03 | [-0.07, 0.13] | 68.70 | 58.70 |
| Time: CRA 30 - 60 | 0.03 | [-0.07, 0.13] | 68.70 | 58.70 |
| Time: CRA 60 - 120 | 0.05 | [-0.15, 0.26] | 68.70 | 30.75 |
| Time: CRV | ||||
| Time: CRV 0 - 30 | -0.05 | [-0.15, 0.05] | 82.80 | 47.65 |
| Time: CRV 30 - 60 | -0.05 | [-0.15, 0.05] | 82.80 | 47.65 |
| Time: CRV 60 - 120 | -0.10 | [-0.30, 0.10] | 82.80 | 22.75 |